发明申请
US20050154013A1 Pressurised metered dose inhalers containing solutions of beta-2 agonists
审中-公开
含有β-2激动剂溶液的加压计量吸入器
- 专利标题: Pressurised metered dose inhalers containing solutions of beta-2 agonists
- 专利标题(中): 含有β-2激动剂溶液的加压计量吸入器
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申请号: US10505861申请日: 2003-02-27
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公开(公告)号: US20050154013A1公开(公告)日: 2005-07-14
- 发明人: Rebecca Davies , David Ganderton , David Lewis , Brian Meakin , Tanya Church , Gaetano Brambilla , Alessandra Ferraris
- 申请人: Rebecca Davies , David Ganderton , David Lewis , Brian Meakin , Tanya Church , Gaetano Brambilla , Alessandra Ferraris
- 申请人地址: IT Parma 43100
- 专利权人: Chiesi Farmaceutici S.p.A.
- 当前专利权人: Chiesi Farmaceutici S.p.A.
- 当前专利权人地址: IT Parma 43100
- 优先权: EP02004786.6 20020301; EP02023589.1 20021023
- 国际申请: PCT/EP03/02004 WO 20030227
- 主分类号: A61K9/12
- IPC分类号: A61K9/12 ; A61K9/00 ; A61K9/72 ; A61K31/00 ; A61K31/167 ; A61K31/4704 ; A61K31/485 ; A61K45/06 ; A61K47/06 ; A61K47/10 ; A61P11/00 ; A61P11/06 ; A61P11/08 ; A61P11/16 ; A61P43/00 ; C07D215/26 ; A61K31/4706 ; A61L9/04
摘要:
The present invention relates to a pharmaceutical formulation for use in the administration of 2(1H)-quinolinone derivatives long-acting β2-agonists by inhalation. In particular this invention relates to a chemically stable highly efficient TA 2005 HFA solution formulation to be administered by pressurised metered dose inhalers (pMDIs) characterized by a deep lung penetration. The invention also relates to methods for the preparation of said formulation and to its use in respiratory diseases such as asthma and chronic obstructive pulmonary disease (COPD).
公开/授权文献
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