发明申请
US20050154013A1 Pressurised metered dose inhalers containing solutions of beta-2 agonists 审中-公开
含有β-2激动剂溶液的加压计量吸入器

Pressurised metered dose inhalers containing solutions of beta-2 agonists
摘要:
The present invention relates to a pharmaceutical formulation for use in the administration of 2(1H)-quinolinone derivatives long-acting β2-agonists by inhalation. In particular this invention relates to a chemically stable highly efficient TA 2005 HFA solution formulation to be administered by pressurised metered dose inhalers (pMDIs) characterized by a deep lung penetration. The invention also relates to methods for the preparation of said formulation and to its use in respiratory diseases such as asthma and chronic obstructive pulmonary disease (COPD).
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