发明申请
- 专利标题： Non-nucleotide compositions and method for inhibiting platelet aggregation
- 专利标题（中）： 非核苷酸组合物和抑制血小板聚集的方法
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申请号： US10971766申请日： 2004-10-21
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公开(公告)号： US20050159388A1公开(公告)日： 2005-07-21
- 发明人: Robert Plourde , Sammy Shaver , Melwyn Abreo , Lorenzo Alfaro-Lopez , Yangbo Feng , Daniel Harvey , Tatyana Khasanova , Chi Tu
- 申请人： Robert Plourde , Sammy Shaver , Melwyn Abreo , Lorenzo Alfaro-Lopez , Yangbo Feng , Daniel Harvey , Tatyana Khasanova , Chi Tu
- 主分类号： A61K31/00
- IPC分类号： A61K31/00 ; A61K31/519 ; A61K31/522 ; A61K31/7076 ; A61K31/727 ; A61K45/06 ; C07D471/04 ; C07D493/04 ; C07D519/00
摘要：
This invention is directed to a method of preventing or treating diseases or conditions associated with platelet aggregation. The method is also directed to a method of treating thrombosis or related disorders. The method comprises administering to a subject a pharmaceutical composition comprising an effective amount of a non-nucleotide compound, preferably a P2Y12 receptor antagonist compound, wherein said amount is effective to inhibit platelet aggregation. The compounds useful for this invention include compounds of general Formulae I and III-XI, or salts, hydrates, and solvates thereof. The present invention also provides novel compounds according to Formulae I and III-XI.