发明申请
- 专利标题: Compounds, compositions and methods
- 专利标题(中): 化合物,组合物和方法
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申请号: US10890829申请日: 2004-07-14
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公开(公告)号: US20050159416A1公开(公告)日: 2005-07-21
- 发明人: Bradley Morgan , Kathleen Elias , Erica Kraynack , Pu-Ping Lu , Fady Malik , Alex Muci , Xiangping Qian , Whitney Smith , Todd Tochimoto , Adam Tomasi , David Morgans
- 申请人: Bradley Morgan , Kathleen Elias , Erica Kraynack , Pu-Ping Lu , Fady Malik , Alex Muci , Xiangping Qian , Whitney Smith , Todd Tochimoto , Adam Tomasi , David Morgans
- 主分类号: A61K
- IPC分类号: A61K20060101 ; A61K31/17 ; A61K31/34 ; A61K31/35 ; A61K31/424 ; A61K31/44 ; A61K31/4439 ; A61K31/4545 ; A61K31/5377 ; C07C273/02 ; C07C275/28 ; C07C275/30 ; C07C275/34 ; C07C275/36 ; C07C275/40 ; C07D207/12 ; C07D211/42 ; C07D213/02 ; C07D213/65 ; C07D213/70 ; C07D213/75 ; C07D217/04 ; C07D401/12 ; C07D405/12 ; C07D413/02 ; C07D413/12 ; C07D417/12 ; C07D498/04 ; C07D513/04 ; C07D41/02 ; C07D43/02 ; C07D45/02
摘要:
Certain substituted urea derivatives selectively modulate the cardiac sarcomere, for example by potentiating cardiac myosin, and are useful in the treatment of systolic heart failure including congestive heart failure.
公开/授权文献
- US07491826B2 Compounds, compositions and methods 公开/授权日:2009-02-17
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