发明申请
- 专利标题： Linear gamma-carboxyglutamate rich conotoxins
- 专利标题（中）： 线性γ-羧基谷氨酸富含芋螺毒素
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申请号： US11018369申请日： 2004-12-22
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公开(公告)号： US20050159586A1公开(公告)日： 2005-07-21
- 发明人: Baldomero Olivera , J. McIntosh , James Garrett , Craig Walker , Maren Watkins , Robert Jones
- 申请人： Baldomero Olivera , J. McIntosh , James Garrett , Craig Walker , Maren Watkins , Robert Jones
- 申请人地址： US UT Salt Lake City US UT Salt Lake City
- 专利权人： University of Utah Research Foundation,Cognetix, Inc.
- 当前专利权人： University of Utah Research Foundation,Cognetix, Inc.
- 当前专利权人地址： US UT Salt Lake City US UT Salt Lake City
- 主分类号： A61K38/00
- IPC分类号： A61K38/00 ; A61P25/18 ; A61P25/24 ; A61P25/28 ; C07K14/435
摘要：
The invention relates to linear γ-carboxyglutamate rich conotoxins, derivatives or pharmaceutically acceptable salts thereof, and uses thereof, including the treatment of neurologic and psychiatric disorders, such as anticonvillsant agents, as neuroprotective agents or for the management of pain. The invention further relates to nucleic acid sequences encoding the conopeptides and encoding propeptides, as well as the propeptides.
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