发明申请
- 专利标题： Production of glucagon like peptide 2 and analogs
- 专利标题（中）： 产生胰高血糖素样肽2和类似物
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申请号： US10993127申请日： 2004-11-22
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公开(公告)号： US20050164930A1公开(公告)日： 2005-07-28
- 发明人: Ken Sasaki , Vanessa Jane Williamson , Alberto de Araujo , Ewa Walczyk
- 申请人： Ken Sasaki , Vanessa Jane Williamson , Alberto de Araujo , Ewa Walczyk
- 专利权人： NPS ALLELIX CORP.
- 当前专利权人： NPS ALLELIX CORP.
- 主分类号： C07K14/605
- IPC分类号： C07K14/605 ; C12N1/21 ; C12N15/74
摘要：
GLP-2 peptides and analogs thereof are produced in high yield and with desired, authentic termini by isolation from a GLP-2 peptide multimer in which at least two units of GLP-2 peptide are coupled through a linker that presents an N-terminal acid cleavage site and a C-terminal enzyme cleavage site. In a specific embodiment, [Gly2]hGLP-2 is produced from a multimeric precursor comprising 2-30 units thereof.
公开/授权文献
- US07829307B2 Production of glucagon-like peptide 2 公开/授权日：2010-11-09
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