The present invention relates to a method of driving a photosensitive device comprising a matrix of photosensitive pixels of the type produced in particular by techniques for depositing semiconductor materials. The invention relates more particularly (but not exclusively) to the driving of such devices used for radiological image detection. The method consists in subjecting the photosensitive pixel during a read phase to a cycle of successive images comprising a useful image preceded by at least one offset image taken at an initial instant. A correction is applied to the useful image, said correction being based on the offset image taken at the initial instant and based on the time (ti) separating the useful image from the offset image taken at the initial instant.