发明申请
- 专利标题: Intravascular delivery of nucleic acid
- 专利标题(中): 核酸的血管内递送
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申请号: US11008856申请日: 2004-12-10
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公开(公告)号: US20050182013A1公开(公告)日: 2005-08-18
- 发明人: Jon Wolff , Vladimir Budker , James Hagstrom , Julia Hegge
- 申请人: Jon Wolff , Vladimir Budker , James Hagstrom , Julia Hegge
- 主分类号: A61K38/12
- IPC分类号: A61K38/12 ; A61K48/00 ; C12N15/87 ; C12N15/85 ; C12N15/88
摘要:
Disclosed is a process for providing for expression of an exogenous nucleic acid in an extravascular parenchymal cell of a mammal. The nucleic acid is inserted into a vessel of a mammal and the permeability of the vessel is increased. Increasing permeability of the vessel allows delivery of the nucleic acid to an extravascular parenchymal cell.
公开/授权文献
- US07015040B2 Intravascular delivery of nucleic acid 公开/授权日:2006-03-21
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