发明申请
- 专利标题: Antibody to bladder cancer nuclear matrix protein and its use
- 专利标题(中): 膀胱癌核基质蛋白的抗体及其用途
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申请号: US11090289申请日: 2005-03-28
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公开(公告)号: US20050186644A1公开(公告)日: 2005-08-25
- 发明人: Robert Getzenberg
- 申请人: Robert Getzenberg
- 专利权人: University of Pittsburgh
- 当前专利权人: University of Pittsburgh
- 主分类号: A61K38/00
- IPC分类号: A61K38/00 ; A61K48/00 ; C07K14/47 ; C07K16/18 ; G01N33/574 ; G01N33/68 ; G01N33/53 ; C07K16/30
摘要:
Nuclear matrix proteins (NMP) which are characterized by a defined expression in tissue are provided. These NMPs are useful markers in diagnosing and monitoring the stage of malignancy of a cell and treating cell proliferative disorders associated with the NMP. Also provided are substantially purified polypeptides and nucleotide sequences encoding the NMPs of the invention.
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