A receiver includes a receiver circuit that decodes multiple signals of interest contained in a composite received signal. The receiver comprises a plurality of successive signal detection stages to detect respective signals contained in the composite received signal. Each detection circuit comprises at least one Generalized RAKE combining circuit and generates a detected signal at an output. Each but the last stage further comprises a signal regeneration circuit that cancels the signal of interest detected by that stage from a stage input signal provided to the next stage such that successive detection of the signals of interest benefits from cumulative cancellation of the previously detected signals.