发明申请
US20050197283A1 Compositions containing beta 2-glycoprotein I for the prevention and/or treatment of vascular disease
审中-公开
含有β2-糖蛋白I的组合物用于预防和/或治疗血管疾病
- 专利标题： Compositions containing beta 2-glycoprotein I for the prevention and/or treatment of vascular disease
- 专利标题（中）： 含有β2-糖蛋白I的组合物用于预防和/或治疗血管疾病
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申请号： US11106665申请日： 2005-04-15
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公开(公告)号： US20050197283A1公开(公告)日： 2005-09-08
- 发明人: Dror Harats , Yehuda Shoenfeld , Niva Yacov , Jacob George
- 申请人： Dror Harats , Yehuda Shoenfeld , Niva Yacov , Jacob George
- 申请人地址： IL Or Yehuda
- 专利权人： Vascular Biogenics Ltd.
- 当前专利权人： Vascular Biogenics Ltd.
- 当前专利权人地址： IL Or Yehuda
- 优先权： IL126447 19981004
- 主分类号： A61K38/17
- IPC分类号： A61K38/17 ; A61K45/06 ; A61K39/00 ; A61K31/401
摘要：
Methods and compositions employing beta2-glycoprotein-1 (β2GPI) or derivatives of β2GPI effective in inducing mucosal tolerance to atheroma related antigens, thus inhibiting inflammatory processes contributing to atheromatous vascular disease and sequalae, are provided. Also provided are articles of manufacture comprising mucosal tolerance inducing amounts of beta2-glycoprotein-1 46 (β2GPI) or derivatives thereof.
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