发明申请
US20050207531A1 Radiation therapy system using interior-point methods and convex models for intensity modulated fluence map optimization
审中-公开
使用内点法和凸模型进行强度调制注量地图优化的放射治疗系统
- 专利标题： Radiation therapy system using interior-point methods and convex models for intensity modulated fluence map optimization
- 专利标题（中）： 使用内点法和凸模型进行强度调制注量地图优化的放射治疗系统
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申请号： US11039331申请日： 2005-01-20
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公开(公告)号： US20050207531A1公开(公告)日： 2005-09-22
- 发明人: James Dempsey , Ravindra Ahuja , Arvind Kumar , Jonathan Li , H. Romeijn
- 申请人： James Dempsey , Ravindra Ahuja , Arvind Kumar , Jonathan Li , H. Romeijn
- 申请人地址： US FL GAINESVILLE
- 专利权人： UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC.
- 当前专利权人： UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC.
- 当前专利权人地址： US FL GAINESVILLE
- 主分类号： A61N5/10
- IPC分类号： A61N5/10
摘要：
A method of determining a treatment plan for intensity modulated radiation treatment (IMRT) divides a three-dimensional volume of a patient into a grid of dose voxels. At least a portion of the dose voxels are designated to belong to at least one target or to at least one critical structure. An ionizing radiation dose as delivered by a plurality of beamlets each having a beamlet intensity is modeled. A non-linear convex voxel-based penalty function model is provided for optimizing a fluence map. The fluence map defines the beamlet intensities for each of the plurality of beamlets. The model is then solved based on defined clinical criteria for the target and the critical structure using an interior point algorithm with dense column handling to obtain a globally optimal fluence map.