发明申请
- 专利标题: Quinoline compound
- 专利标题(中): 喹啉化合物
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申请号: US10493427申请日: 2002-10-24
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公开(公告)号: US20050209213A1公开(公告)日: 2005-09-22
- 发明人: Yuji Ishihara , Makoto Kamata , Shiro Takekawa , Nobuhiro Suzuki , Koki Kato
- 申请人: Yuji Ishihara , Makoto Kamata , Shiro Takekawa , Nobuhiro Suzuki , Koki Kato
- 申请人地址: JP Osaka 541-0045
- 专利权人: Takeda Chemical Industries, Ltd.
- 当前专利权人: Takeda Chemical Industries, Ltd.
- 当前专利权人地址: JP Osaka 541-0045
- 优先权: JP2001-327924 20011025; JP2002-163239 20020604
- 国际申请: PCT/JP02/11045 WO 20021024
- 主分类号: A61K31/4015
- IPC分类号: A61K31/4015 ; A61K31/47 ; A61K31/4709 ; A61K31/496 ; A61K31/5377 ; A61K31/55 ; A61P3/04 ; A61P5/04 ; A61P25/22 ; A61P25/24 ; A61P43/00 ; C07D215/38 ; C07D401/06 ; C07D401/12 ; C07D405/12 ; C07D409/12 ; C07D471/04 ; C07D413/02 ; C07D41/02
摘要:
A compound, which has a melanin-concentrating hormone antagonistic action and useful as an agent for preventing or treating obesity, and which is represented by the formula: wherein Ar is a cyclic group optionally having substituent(s); X is a bond or a spacer having a main chain of 1 to 6 atoms; R1 and R2 are the same or different and each is a hydrogen atom or a hydrocarbon group optionally having substituent(s), or R1 and R2 may form, together with the adjacent nitrogen atom, a nitrogen-containing heterocycle optionally having substituent(s); Y is a divalent hydrocarbon group optionally having substituent(s) (except CO); R3 is a hydrogen atom or a hydrocarbon group optionally having substituent(s); and ring A and ring B may further have substituents, and when ring B further has a substituent, the substituent may be linked to R1 to form a ring, or a salt thereof, or a prodrug thereof, is provided.
公开/授权文献
- US07183415B2 Quinoline compound 公开/授权日:2007-02-27