发明申请
- 专利标题： Rho-kinase inhibitors
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申请号： US11111704申请日： 2005-04-22
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公开(公告)号： US20050209261A1公开(公告)日： 2005-09-22
- 发明人: Dhanapalan Nagarathnam , Jacques Dumas , Holia Hatoum-Mokdad , Stephen Boyer , Hans Pluempe
- 申请人： Dhanapalan Nagarathnam , Jacques Dumas , Holia Hatoum-Mokdad , Stephen Boyer , Hans Pluempe
- 主分类号： C07D239/48
- IPC分类号： C07D239/48 ; A61K31/505 ; A61K31/506 ; A61K31/517 ; A61P7/02 ; A61P9/00 ; A61P9/10 ; A61P9/12 ; A61P11/06 ; A61P15/10 ; A61P19/10 ; A61P25/00 ; A61P25/06 ; A61P25/28 ; A61P27/06 ; A61P35/00 ; A61P43/00 ; C07D401/12 ; C07D401/14 ; C07D43/14
摘要：
Disclosed are compounds and derivatives thereof, their synthesis, and their use as Rho-kinase inhibitors. These compounds are useful for inhibiting tumor growth, treating erectile dysfunction, and treating other indications mediated by Rho-kinase, e.g., coronary heart disease.
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