For carry-on and storage, a combination toothbrush container providing features for selectively venting and sealing a dentifrice dispensing toothbrush for drying bristles and for preventing hardening of toothpaste in the spout opening of the brush head. The toothbrush container consists of a hollow vent-tubing with vent holes near the top and the bottom end, as well as a top vent-cap and a bottom vent-cap. Both vent-caps have corresponding vent holes and can be twisted to open or close the vent holes of the vent-tubing for air circulation or for sealing the toothbrush in the enclosed air environment. Optionally the top vent-cap is attached with a dental floss dispenser having a scissors-like two-blade cutter assembly for automatically severing a dental floss by the closing action of the cutter lid. Besides, the vent-caps may have dual walls for enhancing the sealing function.