发明申请
US20050222207A1 Phosphodiesterase 4 inhibitors, including N-substituted diarylamine analogs
审中-公开
磷酸二酯酶4抑制剂,包括N-取代的二芳基胺类似物
- 专利标题: Phosphodiesterase 4 inhibitors, including N-substituted diarylamine analogs
- 专利标题(中): 磷酸二酯酶4抑制剂,包括N-取代的二芳基胺类似物
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申请号: US11008775申请日: 2004-12-10
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公开(公告)号: US20050222207A1公开(公告)日: 2005-10-06
- 发明人: Richard Schumacher , Allen Hopper , Robert Dunn , Erik Kuester , Ashok Tehim , Thomas Renau , Joan Caroon , Francisco Talamas , Sharada Labadie
- 申请人: Richard Schumacher , Allen Hopper , Robert Dunn , Erik Kuester , Ashok Tehim , Thomas Renau , Joan Caroon , Francisco Talamas , Sharada Labadie
- 主分类号: A61K31/444
- IPC分类号: A61K31/444 ; A61K31/4545 ; C07D213/74 ; C07D213/75 ; C07D277/28 ; C07D401/12 ; C07D405/12 ; C07D405/14 ; C07D41/14
摘要:
PDE4 inhibition is achieved by novel compounds, e.g., N-substituted diarylamine analogs. The compounds of the present invention are of Formula I: wherein A, B, D, R1, R2, R3 and R4 are as defined herein.
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