发明申请
- 专利标题： Antibodies to erythropoietin receptor and uses thereof
- 专利标题（中）： 促红细胞生成素受体的抗体及其用途
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申请号： US10822306申请日： 2004-04-12
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公开(公告)号： US20050227289A1公开(公告)日： 2005-10-13
- 发明人: Edward Reilly , Susan Lacy , Emma Fung , Jonathan Belk , Michael Roguska
- 申请人： Edward Reilly , Susan Lacy , Emma Fung , Jonathan Belk , Michael Roguska
- 主分类号： A61K39/395
- IPC分类号： A61K39/395 ; C07K16/28 ; C12N5/10 ; C12N15/13 ; C12N15/63 ; C12Q1/70 ; G01N33/53
摘要：
The present invention relates to antibodies and antigen-binding portions thereof that bind to and activate an erythropoietin receptor. The invention also relates to nucleic acid sequences encoding such antibodies and antigen-binding portions. The present invention further relates to methods of activating the endogenous activity of an erythropoietin receptor in a mammal using said antibodies and antigen-binding portions, methods of treatment, as well as pharmaceutical compositions comprising said antibodies and antigen-binding portions.
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