- 专利标题： Quorum sensing signaling in bacteria
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申请号： US11014621申请日： 2004-12-15
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公开(公告)号： US20050227345A1公开(公告)日： 2005-10-13
- 发明人: Marvin Whiteley , Kimberly Lee , E. Greenberg , Ute Muh
- 申请人： Marvin Whiteley , Kimberly Lee , E. Greenberg , Ute Muh
- 申请人地址： US CA San Diego 92121 US IA Iowa City 52242
- 专利权人： Aurora Biosciences Corporation,UNIV OF IOWA RESEARCH FOUNDATION
- 当前专利权人： Aurora Biosciences Corporation,UNIV OF IOWA RESEARCH FOUNDATION
- 当前专利权人地址： US CA San Diego 92121 US IA Iowa City 52242
- 主分类号： C07K14/21
- IPC分类号： C07K14/21 ; C12N1/21 ; C07H21/04 ; C12N15/74
摘要：
The invention provides methods for identifying a modulator of quorum sensing signaling in bacteria, and for identifying a quorum sensing controlled gene in bacteria. In addition, the invention provides quorum sensing controlled genetic loci in Pseudomas aeruginosa. Novel indicator strains and vectors for engineering the strains for use in the method of the invention are also provided.
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