- 专利标题： Substituted hydroxyethylamine aspartyl protease inhibitors
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申请号： US11075312申请日： 2005-03-09
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公开(公告)号： US20050239836A1公开(公告)日： 2005-10-27
- 发明人: Varghese John , Michel Maillard , John Tucker , Jose Aquino , Barbara Jagodzinska , Louis Brogley , Jay Tung , Simeon Bowers , Darren Dressen , Gary Probst , Neerav Shah
- 申请人： Varghese John , Michel Maillard , John Tucker , Jose Aquino , Barbara Jagodzinska , Louis Brogley , Jay Tung , Simeon Bowers , Darren Dressen , Gary Probst , Neerav Shah
- 主分类号： A61K31/382
- IPC分类号： A61K31/382 ; A61K31/453 ; C07D207/32 ; C07D207/325 ; C07D233/54 ; C07D257/04 ; C07D335/06 ; C07D403/12 ; C07D405/12 ; C07D419/12 ; C07D49/02
摘要：
The invention relates to novel compounds and also to methods of treating at least one disease, disorder, or condition associated with amyloidosis using such compounds. Amyloidosis refers to a collection of diseases, disorders, and conditions associated with abnormal deposition of A-beta protein.