发明申请
- 专利标题: Modulation of transthyretin expression
- 专利标题(中): 转甲状腺素蛋白表达的调节
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申请号: US11097928申请日: 2005-04-01
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公开(公告)号: US20050244869A1公开(公告)日: 2005-11-03
- 发明人: Vickie Brown-Driver , Ravi Jain
- 申请人: Vickie Brown-Driver , Ravi Jain
- 主分类号: A61K48/00
- IPC分类号: A61K48/00 ; C07H21/02 ; C12N15/113 ; C12Q1/68
摘要:
Compounds, compositions and methods are provided for modulating the expression of transthyretin. The compositions comprise oligonucleotides, targeted to nucleic acid encoding transthyretin. Methods of using these compounds for modulation of transthyretin expression and for diagnosis and treatment of diseases and conditions associated with expression of transthyretin are provided.
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