发明申请
- 专利标题: New methods
- 专利标题(中): 新方法
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申请号: US10996589申请日: 2004-11-26
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公开(公告)号: US20050245540A1公开(公告)日: 2005-11-03
- 发明人: Nobuaki Takeshita , Takayuki Inoue
- 申请人: Nobuaki Takeshita , Takayuki Inoue
- 申请人地址: JP Osaka
- 专利权人: FUJISAWA PHARMACEUTICAL CO., LTD.
- 当前专利权人: FUJISAWA PHARMACEUTICAL CO., LTD.
- 当前专利权人地址: JP Osaka
- 优先权: AU2003906809 20031209
- 主分类号: A61K31/454
- IPC分类号: A61K31/454 ; A61K31/496
摘要:
This invention relates to a method for preventing and/or treating bone diseases which comprises administering a potentiator of TGF-beta activity such as the compound of the formula [I] or pharmaceutically acceptable salts thereof to human being or animals. wherein R1 is hydrogen, etc., R2 is optionally substituted ar(lower)alkyl or optionally substituted heterocyclic(lower)alkyl, etc., R3 is hydrogen, optionally substituted hydroxy, etc., R4 is hydrogen or lower alkyl, and X is CH or N.