发明申请
- 专利标题： Ortho substituted aryl or heteroaryl amide compounds
- 专利标题（中）： 正构取代的芳基或杂芳基酰胺化合物
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申请号： US11118646申请日： 2005-04-29
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公开(公告)号： US20050250818A1公开(公告)日： 2005-11-10
- 发明人: Hiroki Koike , Yukari Matsumoto , Kazunari Nakao , Yoshiyuki Okumura , Tatsuya Yamagishi
- 申请人： Hiroki Koike , Yukari Matsumoto , Kazunari Nakao , Yoshiyuki Okumura , Tatsuya Yamagishi
- 专利权人： Pfizer Inc
- 当前专利权人： Pfizer Inc
- 主分类号： A61K31/195
- IPC分类号： A61K31/195 ; A61K31/4415 ; C07C235/60 ; C07C255/54 ; C07D213/61 ; C07D213/82 ; C07D213/89 ; C07D261/08 ; C07D307/12 ; C07D307/42 ; C07D309/06
摘要：
This invention provides a compound of the formula (I): wherein X represents a carbon atom or the like: Y represents imino, or the like: Z represents a hydrogen atom or the like: R1 represents an alkyl group having from 1 to 6 carbon atoms or the like: R2 and R3 independently represents a hydrogen atom or the like. These compounds are useful for the treatment of disease conditions mediated by prostaglandin such as pain, or the like in mammalian. This invention also provides a pharmaceutical composition comprising the above compound.