发明申请
- 专利标题： Anti human ovarian cancer-anti cd3 bispecific antibody
- 专利标题（中）： 抗人卵巢癌抗CD3双特异性抗体
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申请号： US10478345申请日： 2002-05-23
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公开(公告)号： US20050255115A1公开(公告)日： 2005-11-17
- 发明人: Hualiang Huang , Xin Jiang , Min Fang , Jie Feng , Ping Zhou , Xiaocong Yu , Qing Lin
- 申请人： Hualiang Huang , Xin Jiang , Min Fang , Jie Feng , Ping Zhou , Xiaocong Yu , Qing Lin
- 优先权： CN01118247.4 20010524
- 国际申请： PCT/CN02/00347 WO 20020523
- 主分类号： A61K39/395
- IPC分类号： A61K39/395 ; C07K16/28 ; C07K16/30 ; C07K19/00 ; C12N15/13 ; C12N15/62 ; C12N15/63 ; C12P21/08 ; G01N33/574 ; C12N5/06
摘要：
The present invention provides an anti-ovarian cancer bispecific antibody. Said antibody includes two polypeptide domains connected by a polypeptide linker, one is anti-ovarian cancer antibody, or its Fab fragment, single complementarity determining region (CDR) antibody or single chain Fv (scFv) and the other is anti-CD3 antibody, or its Fab fragment, single CDR antibody or scFv. The present invention also provides DNA sequences encoding said antibody, an expression vector containing said DNA sequence, and a host cell containing said expression vector.
公开/授权文献
- US07262276B2 Anti human ovarian cancer-anti CD3 bispecific antibody 公开/授权日：2007-08-28
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