发明申请
US20050267025A1 Compositions and methods for treatment of infectious and inflammatory diseases
审中-公开
用于治疗感染性和炎性疾病的组合物和方法
- 专利标题： Compositions and methods for treatment of infectious and inflammatory diseases
- 专利标题（中）： 用于治疗感染性和炎性疾病的组合物和方法
-
申请号： US11083624申请日： 2005-03-18
-
公开(公告)号： US20050267025A1公开(公告)日： 2005-12-01
- 发明人: John Ho
- 申请人： John Ho
- 主分类号： A61K39/00
- IPC分类号： A61K39/00 ; C07K14/35 ; C12N1/21 ; C12Q1/68 ; G01N33/569 ; A61K38/17
摘要：
The present invention relates to a vaccine for preventing Mycobacterium tuberculosis infection that contains a polypeptide isolated from Mycobacterium tuberculosis that suppresses the immune response and induces IL-10 in a subject infected with Mycobacterium tuberculosis, and to methods of treating an inflammatory condition in a mammal, vaccinating a mammal against infection by Mycobacterium tuberculosis, and treating a mammal for infection by Mycobacterium tuberculosis, which involve providing a nucleic acid molecule encoding the polypeptide isolated from Mycobacterium tuberculosis that suppresses the immune response and induces IL-10 in a subject infected with Mycobacterium tuberculosis, or the polypeptide itself, and administering the nucleic acid molecule or its encoded polypeptide to a mammal.
信息查询
