发明申请
- 专利标题: Novel oxazole derivatives
- 专利标题(中): 新型恶唑衍生物
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申请号: US11183360申请日: 2005-07-18
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公开(公告)号: US20050267180A1公开(公告)日: 2005-12-01
- 发明人: Alfred Binggeli , Markus Boehringer , Uwe Grether , Hans Hilpert , Georges Hirth , Hans-Peter Maerki , Markus Meyer , Peter Mohr , Fabienne Ricklin
- 申请人: Alfred Binggeli , Markus Boehringer , Uwe Grether , Hans Hilpert , Georges Hirth , Hans-Peter Maerki , Markus Meyer , Peter Mohr , Fabienne Ricklin
- 优先权: EP02022286.5 20021007
- 主分类号: A61K31/421
- IPC分类号: A61K31/421 ; A61P3/10 ; C07D263/32
摘要:
The present invention relates to compounds of formula (I) wherein wherein R1, R2, R3, R4, R5, R6 and n are as described herein. The compounds of the present invention can be used as medicaments for the treatment and/or prevention of diseases which are modulated by PPARα and/or PPARγ agonists. Examples of such diseases are diabetes, particularly non-insulin dependent diabetes mellitus, elevated blood pressure, increased lipid and cholesterol levels, atherosclerotic diseases, metabolic syndrome, endothelial dysfunction, procoagulant state, dyslipidemia, polycystic ovary syndrome, inflammatory diseases (such as e.g. crown disease, inflammatory bowel disease, collitis, pancreatitis, cholestasis/fibrosis of the liver, and diseases that have an inflammatory component such as e.g. Alzheimer's disease or impaired/improvable cognitive function) and proliferative diseases.
公开/授权文献
- US07348349B2 Oxazole derivatives 公开/授权日:2008-03-25
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