发明申请
US20050267185A1 1,2,4-triazole derivatives, compositions, process of making and methods of use
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1,2,4-三唑衍生物,组合物,制备方法和使用方法
- 专利标题: 1,2,4-triazole derivatives, compositions, process of making and methods of use
- 专利标题(中): 1,2,4-三唑衍生物,组合物,制备方法和使用方法
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申请号: US11186519申请日: 2005-07-21
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公开(公告)号: US20050267185A1公开(公告)日: 2005-12-01
- 发明人: Joseph Marino , Scott Thompson , Daniel Veber
- 申请人: Joseph Marino , Scott Thompson , Daniel Veber
- 专利权人: SmithKline Beecham Corporation
- 当前专利权人: SmithKline Beecham Corporation
- 主分类号: A61K31/4196
- IPC分类号: A61K31/4196 ; A61K31/422 ; A61K31/4245 ; A61K31/427 ; A61K31/4439 ; A61K31/4709 ; A61P3/04 ; A61P9/10 ; A61P9/14 ; A61P17/06 ; A61P19/02 ; A61P29/00 ; A61P35/00 ; A61P43/00 ; C07D249/12 ; C07D249/14 ; C07D401/12 ; C07D403/12 ; C07D405/12 ; C07D409/12 ; C07D413/12 ; C07D417/12
摘要:
Compounds of this invention are non-peptide, reversible inhibitors of type 2 methionine aminopeptidase, useful in treating conditions mediated by angiogenesis, such as cancer, haemangioma, proliferative retinopathy, rheumatoid arthritis, atherosclerotic neovascularization, psoriasis, ocular neovascularization and obesity.
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