发明申请
US20050276809A1 Function of autophagy genes in cell death 失效
自噬基因在细胞死亡中的功能

Function of autophagy genes in cell death
摘要:
The present invention relates to a new molecular pathway in which activation of the receptor-interacting protein (RIP, a serine-threonine kinase) and Jun N-terminal kinase induce cell death with the morphology of autophagy. Further, autophagic death is induced by caspase 8 inhibition and expression of the mammalian genes ATG7 and beclin.
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