发明申请
- 专利标题: Analogs of gastric inhibitory polypeptide and their use of treatment of diabetes
- 专利标题(中): 胃抑制多肽的类似物及其治疗糖尿病的用途
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申请号: US11090825申请日: 2005-03-25
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公开(公告)号: US20050277590A1公开(公告)日: 2005-12-15
- 发明人: Finbarr O'Harte , Peter Flatt
- 申请人: Finbarr O'Harte , Peter Flatt
- 申请人地址: GB Coleraine
- 专利权人: Uutech Limited
- 当前专利权人: Uutech Limited
- 当前专利权人地址: GB Coleraine
- 优先权: GBGB9917565.5 19990729; GBGB9907216.7 19990329
- 主分类号: A61K38/00
- IPC分类号: A61K38/00 ; A61K38/22 ; A61K38/26 ; A61P5/48 ; C07K14/575
摘要:
The present invention provides peptides which stimulate the release of insulin. The peptides, based on GIP 1-42 include substitutions and/or modifications which enhance and influence secretion and/or have enhanced resistance to degradation. The invention also provides a process of N terminally modifying GIP and the use of the peptide analogues for treatment of diabetes.
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