- 专利标题： Antagonists of melanin concentrating hormone effects on the melanin concentrating hormone receptor
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申请号： US11022453申请日： 2004-12-22
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公开(公告)号： US20050277638A1公开(公告)日： 2005-12-15
- 发明人: Andrew Souers , Christine Collins , Ju Gao , Andrew Judd , Philip Kym , Mathew Mulhern , Hing Sham , Dariusz Wodka
- 申请人： Andrew Souers , Christine Collins , Ju Gao , Andrew Judd , Philip Kym , Mathew Mulhern , Hing Sham , Dariusz Wodka
- 主分类号： A61K31/416
- IPC分类号： A61K31/416 ; A61K31/5377 ; C07D231/56 ; C07D401/04 ; C07D401/06 ; C07D403/06 ; C07D403/14 ; C07D405/12 ; C07D409/04 ; C07D409/12 ; C07D413/02 ; C07D413/04
摘要：
The present invention relates to the antagonism of the effects of melanin-concentrating hormone (MCH) through the melanin concentrating hormone receptor which is useful for the prevention or treatment of eating disorders, weight gain, obesity, abnormalities in reproduction and sexual behavior, thyroid hormone secretion, diuresis and water/electrolyte homeostasis, sensory processing, memory, sleeping, arousal, anxiety, depression, seizures, neurodegeneration and psychiatric disorders.
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