发明申请
US20050287558A1 SNPs of apolipoprotein B and modulation of their expression
审中-公开
载脂蛋白B的单核苷酸多态性及其表达调控
- 专利标题： SNPs of apolipoprotein B and modulation of their expression
- 专利标题（中）： 载脂蛋白B的单核苷酸多态性及其表达调控
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申请号： US11124020申请日： 2005-05-05
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公开(公告)号： US20050287558A1公开(公告)日： 2005-12-29
- 发明人: Rosanne Crooke , Mark Graham , Steven Mah
- 申请人： Rosanne Crooke , Mark Graham , Steven Mah
- 主分类号： A61K48/00
- IPC分类号： A61K48/00 ; C07H21/04 ; C12Q1/68
摘要：
Compounds, compositions and methods are provided for modulating the expression of apolipoprotein B. The compositions comprise oligonucleotides, targeted to nucleic acid encoding apolipoprotein B. Methods of using these compounds for modulation of apolipoprotein B expression and for diagnosis and treatment of diseases and conditions associated with expression of apolipoprotein B are provided.