发明申请
US20060009443A1 Fused heterocyclic compounds and their use as metabotropic glutamate receptor antagonists
失效
稠合杂环化合物及其作为代谢型谷氨酸受体拮抗剂的用途
- 专利标题： Fused heterocyclic compounds and their use as metabotropic glutamate receptor antagonists
- 专利标题（中）： 稠合杂环化合物及其作为代谢型谷氨酸受体拮抗剂的用途
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申请号： US11060560申请日： 2005-02-18
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公开(公告)号： US20060009443A1公开(公告)日： 2006-01-12
- 发明人: David Wensbo , Martin Johansson , Alexander Minidis , Karin Staaf , Annika Kers , Louise Edwards , Methvin Isaac , Tom Stefanac , Abdelmalik Slassi , Don McLeod , Tao Xin
- 申请人： David Wensbo , Martin Johansson , Alexander Minidis , Karin Staaf , Annika Kers , Louise Edwards , Methvin Isaac , Tom Stefanac , Abdelmalik Slassi , Don McLeod , Tao Xin
- 专利权人： AstraZeneca AB,NPS Pharmaceuticals Inc.
- 当前专利权人： AstraZeneca AB,NPS Pharmaceuticals Inc.
- 主分类号： A61K31/407
- IPC分类号： A61K31/407
摘要：
The present invention is directed to compounds of formula I: wherein X1, X2, X3, X4, X5, X6, X7, X8, X9, X10, R1, R2, R3, R4, and n are as defined for formula I in the description. The invention also relates to processes for the preparation of the compounds and to new intermediates employed in the preparation, pharmaceutical compositions containing the compounds, and to the use of the compounds in therapy.
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