A hospital layout comprising a plurality of adjacent OR/intervention rooms (46, 48) uniquely configured and equipped to perform surgical and other interventional procedures, with adjacent intubation rooms (52) configured and equipped to prepare patients for procedures to occur in the OR/intervention rooms and at least one extubation room (54) adjacent the OR/intervention rooms, configured and equipped to post-intervention awaken and extubate patients. A plurality of universal patient rooms (40) are located adjacent the OR/intervention rooms and universal patient rooms, and are configured and equipped to admit patients for surgery/intervention, prepare patients for surgery/intervention, allow patients to recover post-intervention, and discharge patients post-recovery.