发明申请
- 专利标题: Immediate release pharmaceutical formulation
- 专利标题(中): 立即释放药物制剂
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申请号: US10516423申请日: 2003-05-27
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公开(公告)号: US20060014734A1公开(公告)日: 2006-01-19
- 发明人: Susanna Alami , Tord Inghardt , Anders Magnusson , Carl-Gustaf Sigfridsson , Mikael Thune
- 申请人: Susanna Alami , Tord Inghardt , Anders Magnusson , Carl-Gustaf Sigfridsson , Mikael Thune
- 优先权: SE0201658-2 20020531
- 国际申请: PCT/SE03/00857 WO 20030527
- 主分类号: A61K31/397
- IPC分类号: A61K31/397 ; A61K9/20
摘要:
According to the present invention there is provided an immediate release pharmaceutical formulation comprising, as active ingredient, a compound of formula (I): wherein R1 represents C1-2 alkyl substituted by one or more fluoro substituents; R2 represents hydrogen, hydroxy, methoxy or ethoxy; and n represents 0, 1 or 2; or a pharmaceutically acceptable salt thereof; and a pharmaceutically acceptable diluent or carrier; provided that when the active ingredient is other than in the form of a salt the formulation does not solely contain: a solution of one active ingredient and water, a solution of one active ingredient and dimethylsulphoxide; or a solution of one active ingredient in a mixture of ethanol:PEG 660 12-hydroxy stearate:water 5:5:90; such formulations being of use for the treatment of a cardiovascular disorder.
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