- 专利标题： Nicotinamide derivatives useful as PDE4 inhibitors
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申请号： US11229395申请日： 2005-09-16
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公开(公告)号： US20060014780A1公开(公告)日： 2006-01-19
- 发明人: Simon Bailey , Elisabeth Gautier , Alan Henderson , Thomas Magee , Anthony Marfat , John Mathias , Dale McLeod , Sandra Monaghan , Blanda Stammen
- 申请人： Simon Bailey , Elisabeth Gautier , Alan Henderson , Thomas Magee , Anthony Marfat , John Mathias , Dale McLeod , Sandra Monaghan , Blanda Stammen
- 专利权人： Pfizer Inc
- 当前专利权人： Pfizer Inc
- 优先权： GB0203196.1 20020211; GB0220999.7 20020910; GB0224453.1 20021021; GB0227139.3 20021120
- 主分类号： A61K31/46
- IPC分类号： A61K31/46 ; A61K31/4545 ; A61K31/4433 ; A61K31/4415 ; C07D405/02 ; C07D401/02 ; C07D453/02
摘要：
The invention relates to nicotinamide derivatives and to processes for the preparation of, intermediates used in the preparation of, compositions containing and the uses of, such derivatives. The nicotinamide derivatives according to the present invention are useful in numerous diseases, disorders and conditions, in particular inflammatory, allergic, respiratory diseases, disorders and conditions, as well as wounds.
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