发明申请
- 专利标题： Heteroclitic analogs and related methods
- 专利标题（中）： 异构体类似物和相关方法
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申请号： US10510101申请日： 2003-04-07
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公开(公告)号： US20060018915A1公开(公告)日： 2006-01-26
- 发明人: Glenn Ishioka , John Fikes , Shabnam Tangri , Alessandro Sette
- 申请人： Glenn Ishioka , John Fikes , Shabnam Tangri , Alessandro Sette
- 国际申请： PCT/US03/10571 WO 20030407
- 主分类号： A61K39/00
- IPC分类号： A61K39/00 ; C07H21/04 ; C12P21/06 ; C07K14/72
摘要：
Heteroclitic analogs of class I epitopes are prepared by providing conservative, semi-conservative, or non-conservative amino acid substitutions at positions 3 and/or 4 and/or 5 and/or 6 and/or 7 and/or 8 and/or 9 and/or 10 of these epitopes. The analogs are useful in eliciting immune responses with respect to the corresponding wild-type epitopes.
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