发明申请
US20060019297A1 Glyceraldehyde-3-phosphate dehydrogenase and phosphoglycerate mutase regulatory sequences for gene expression in oleaginous yeast
失效
甘油醛-3-磷酸脱氢酶和磷酸甘油酸变位酶调节序列用于含油酵母中的基因表达
- 专利标题： Glyceraldehyde-3-phosphate dehydrogenase and phosphoglycerate mutase regulatory sequences for gene expression in oleaginous yeast
- 专利标题（中）： 甘油醛-3-磷酸脱氢酶和磷酸甘油酸变位酶调节序列用于含油酵母中的基因表达
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申请号： US11183664申请日： 2005-07-18
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公开(公告)号： US20060019297A1公开(公告)日： 2006-01-26
- 发明人: Stephen Picataggio , Quinn Zhu
- 申请人： Stephen Picataggio , Quinn Zhu
- 主分类号： C12Q1/68
- IPC分类号： C12Q1/68 ; C12P21/06 ; C12N1/18 ; C12N15/74
摘要：
The regulatory sequences associated with the Yarrowia lipolytica glyceraldehyde-3-phosphate dehydrogenase (gpd) and phosphoglycerate mutase (gpm) genes have been found to be particularly effective for the expression of heterologous genes in oleaginous yeast. The promoter regions of the invention, intron and enhancer have been shown to drive high-level expression of genes involved in the production of ω-3 and ω-6 fatty acids.
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