发明申请
US20060034828A1 Immunoglobulins comprising predominantly a GlcNAcMAN5GLCNAC2 glycoform
审中-公开
主要包含GlcNAcMAN5GLCNAC2糖型的免疫球蛋白
- 专利标题： Immunoglobulins comprising predominantly a GlcNAcMAN5GLCNAC2 glycoform
- 专利标题（中）： 主要包含GlcNAcMAN5GLCNAC2糖型的免疫球蛋白
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申请号： US11187066申请日： 2005-07-21
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公开(公告)号： US20060034828A1公开(公告)日： 2006-02-16
- 发明人: Tillman Gerngross , Huijuan Li , Stefan Wildt
- 申请人： Tillman Gerngross , Huijuan Li , Stefan Wildt
- 主分类号： A61K39/395
- IPC分类号： A61K39/395 ; C07H21/04 ; C12P21/06
摘要：
The present invention relates to immunoglobulin glycoprotein compositions having predominant N-glycan structures on an immunoglobulin glycoprotein which confer a specific effector function. Additionally, the present invention relates to pharmaceutical compositions comprising an antibody having a particular enriched N-glycan structure, wherein said N-glycan structure is GlcNAcMan5GlcNAc2.