发明申请
- 专利标题: Azaindole kinase inhibitors
- 专利标题(中): Azaindole激酶抑制剂
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申请号: US11214267申请日: 2005-08-29
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公开(公告)号: US20060058304A1公开(公告)日: 2006-03-16
- 发明人: Rajeev Bhide , Rejean Ruel , Carl Thibault , Alexandre L'Heureux
- 申请人: Rajeev Bhide , Rejean Ruel , Carl Thibault , Alexandre L'Heureux
- 主分类号: A61K31/53
- IPC分类号: A61K31/53 ; C07D487/04
摘要:
The present invention provides compounds of formula I, and pharmaceutically acceptable salts thereof. The formula I compounds inhibit the tyrosine kinase activity of growth factor receptors such as VEGFR-2 and FGFR-1, thereby making them useful as anti-cancer agents. The formula I compounds are also useful for the treatment of other diseases associated with signal transduction pathways operating through growth factor receptors.