发明申请
- 专利标题: Condensed imidazole derivatives
- 专利标题(中): 缩合咪唑衍生物
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申请号: US11212407申请日: 2005-08-26
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公开(公告)号: US20060063787A1公开(公告)日: 2006-03-23
- 发明人: Seiji Yoshikawa , Eita Emori , Fumiyoshi Matsuura , Richard Clark , Hironori Ikuta , Kazunobu Kira , Nobuyuki Yasuda , Tadashi Nagakura , Kazuto Yamazaki
- 申请人: Seiji Yoshikawa , Eita Emori , Fumiyoshi Matsuura , Richard Clark , Hironori Ikuta , Kazunobu Kira , Nobuyuki Yasuda , Tadashi Nagakura , Kazuto Yamazaki
- 申请人地址: JP Bunkyo-ku
- 专利权人: Eisai Co., Ltd.
- 当前专利权人: Eisai Co., Ltd.
- 当前专利权人地址: JP Bunkyo-ku
- 优先权: JP2002-307750 20021023; JP2002-209373 20020718; JP2002-166069 20020606
- 主分类号: A61K31/522
- IPC分类号: A61K31/522 ; C07D473/02 ; A61K31/4745 ; C07D471/02
摘要:
The present invention is related to compounds represented by the following formula, or salts or hydrates thereof wherein, T1 represents a 4- to 12-membered heterocyclic group containing one or two nitrogen atoms in the ring, which is a monocyclic or bicyclic structure that may have one or more substituents; X represents a C1-6 alkyl group which may have one or more substituents, or such; Z1 and Z2 each independently represent a nitrogen atom or a group represented by the formula —CR2—; R1 and R2 independently represent a hydrogen atom, a C1-6 alkyl group which may have one or more substituents, or a C1-6 alkoxy group which may have one or more substituents, or such. These are novel compounds that exhibit an excellent DPPIV-inhibiting activity.