发明申请
- 专利标题： Ring-closing metathesis process in supercritical fluid
- 专利标题（中）： 超临界流体闭环复分解过程
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申请号： US11222882申请日： 2005-09-09
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公开(公告)号： US20060063915A1公开(公告)日： 2006-03-23
- 发明人: Fabrice Gallou , Nathan Yee
- 申请人： Fabrice Gallou , Nathan Yee
- 申请人地址： DE Ingelheim
- 专利权人： Boehringer Ingelheim International GmbH
- 当前专利权人： Boehringer Ingelheim International GmbH
- 当前专利权人地址： DE Ingelheim
- 主分类号： C07K5/12
- IPC分类号： C07K5/12
摘要：
Disclosed is a process for preparing a compound of formula I comprising cyclizing a diene compound of formula III in the presence of a ruthenium catalyst in a suitable organic solvent, wherein the process is performed in a gaseous fluid at supercritical or near-supercritical conditions: The compounds of formula (I) are active agents for the treatment of hepatitis C viral (HCV) infections or are intermediates useful for the preparation of anti-HCV agents.
公开/授权文献
- US07189844B2 Ring-closing metathesis process in supercritical fluid 公开/授权日：2007-03-13
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