A drug delivery device for placement in a body includes a drug core comprising a pharmaceutically active agent, and a holder that holds the drug core. The holder is made of a material impermeable to passage of the active agent and includes at least one opening for passage of the pharmaceutically agent therethrough to eye tissue. The holder is continuous with the top through a continuous loop. The continuous loop may be reinforced and sized to provide a point from which the device can be anchored when implanted.