发明申请
- 专利标题： (Arylamidoanilino)nitroethylene compounds
- 专利标题（中）： （芳基酰氨基苯胺基）硝基乙烯化合物
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申请号： US11227697申请日： 2005-09-15
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公开(公告)号： US20060069121A1公开(公告)日： 2006-03-30
- 发明人: Andrew Crew , An-Hu Li , Bijoy Panicker
- 申请人： Andrew Crew , An-Hu Li , Bijoy Panicker
- 主分类号： A61K31/4709
- IPC分类号： A61K31/4709 ; C07D409/14
摘要：
Compounds represented by Formula (I): or a pharmaceutically acceptable salt or N-oxide thereof, wherein A, Q, Y, R1, R2, and R5 are defined herein, are useful in the treatment of tumors and cancers such as mastocytosis/mast cell leukemia, gastrointestinal stromal tumors (GIST), germ cell tumors, small cell lung carcinoma (SCLC), sinonasal natural killer/T-cell lymphoma, testicular cancer (seminoma), thyroid carcinoma, malignant melanoma, ovarian carcinoma, adenoid cystic carcinoma, acute myelogenous leukemia (AML), breast carcinoma, pediatric T-cell acute lymphoblastic leukemia, neuroblastoma, mast cell leukemia, angiosarcoma, anaplastic large cell lymphoma, endometrial carcinoma, and prostate carcinoma.
公开/授权文献
- US07618965B2 (Arylamidoanilino)nitroethylene compounds 公开/授权日：2009-11-17
信息查询
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