发明申请
US20060074040A1 Synergistic stimulation of the immune system using immunostimulatory oligonucleotides and/or immunomer compounds in conjunction with cytokines and/or chemotherapeutic agents or radiation therapy
审中-公开
使用免疫刺激性寡核苷酸和/或免疫化合物与细胞因子和/或化学治疗剂或放射治疗联合使用免疫系统的协同刺激
- 专利标题： Synergistic stimulation of the immune system using immunostimulatory oligonucleotides and/or immunomer compounds in conjunction with cytokines and/or chemotherapeutic agents or radiation therapy
- 专利标题（中）： 使用免疫刺激性寡核苷酸和/或免疫化合物与细胞因子和/或化学治疗剂或放射治疗联合使用免疫系统的协同刺激
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申请号： US10892550申请日： 2004-07-15
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公开(公告)号： US20060074040A1公开(公告)日： 2006-04-06
- 发明人: Ekambar Kandimalla , Sudhir Agrawal
- 申请人： Ekambar Kandimalla , Sudhir Agrawal
- 专利权人： Hybridon, Inc.
- 当前专利权人： Hybridon, Inc.
- 主分类号： A61K48/00
- IPC分类号： A61K48/00 ; A61K38/20 ; A61N5/00
摘要：
The invention provides optimized methods and compositions for enhancing the immune response caused by immunostimulatory compounds used for the treatment of disease such as, but not limited to, treatment of cancer, autoimmune disorders, asthma, respiratory allergies, food allergies and infectious diseases in a patient. The optimized methods according to the invention provide synergy between the therapeutic effects of immunostimulatory oligonucleotides and immunomer compounds in accordance with the invention, and the therapeutic effect of cytokine immunotherapy and/or chemotherapeutic agents and/or radiation.
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