The invention provides a system for treating a vascular condition, a method of manufacturing the system, and a method for using the system to deliver a therapeutic agent to a desired location in a bodily vessel. The system comprises a tubular inner member received in a lumen of an elongated catheter shaft and extending beyond a distal end of the catheter shaft. The system includes at least one inflatable balloon positioned between distal and proximal perfusion ports. At least a portion of the balloon is disposed on the inner member, at least a portion of the inner member underlying the balloon having a wall thickness between about 0.0015 inch and 0.0025 inch and an inner diameter between about 0.020 inch and 0.040 inch. A stent is removably coupled to the balloon. A therapeutic agent is disposed on at least a portion of the stent.