发明申请
- 专利标题： Opioid metallopeptide compositions and methods
- 专利标题（中）： 阿片类金属肽组合物和方法
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申请号： US11291389申请日： 2005-12-01
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公开(公告)号： US20060083685A1公开(公告)日： 2006-04-20
- 发明人: Shubh Sharma , Wei Yang , Hui-Zhi Cai
- 申请人： Shubh Sharma , Wei Yang , Hui-Zhi Cai
- 申请人地址： US NJ Cranbury
- 专利权人： Palatin Technologies, Inc.
- 当前专利权人： Palatin Technologies, Inc.
- 当前专利权人地址： US NJ Cranbury
- 主分类号： A61K51/00
- IPC分类号： A61K51/00 ; C40B40/10 ; C07K7/06
摘要：
Metallopeptides and metallopeptide combinatorial libraries specific for opioid receptors are provided, for use in biological, pharmaceutical and related applications. The metallopeptides and combinatorial libraries are made of peptides, peptidomimetics and peptide-like constructs, in which the peptide, peptidomimetic or construct is conformationally fixed in a biologically active configuration specific for one or more opioid receptors on complexation of a metal ion-binding portion thereof with a metal ion.