发明申请
- 专利标题： Piperazine derivative
- 专利标题（中）： 哌嗪衍生物
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申请号： US10499011申请日： 2002-12-19
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公开(公告)号： US20060084657A1公开(公告)日： 2006-04-20
- 发明人: Atsuro Nakazato , Takaaki Ishii , Dai Nozawa
- 申请人： Atsuro Nakazato , Takaaki Ishii , Dai Nozawa
- 优先权： JP2001-389419 20011221
- 国际申请： PCT/JP02/13317 WO 20021219
- 主分类号： A61K31/496
- IPC分类号： A61K31/496 ; A61K31/497 ; A61K31/506 ; A61K31/517 ; C07D403/14
摘要：
A piperazine derivative represented by the formula (1): wherein n is an integer of 1 to 8; R1 represents hydrogen or C1-10 alkyl; A represents CH or nitrogen; Ar1 represents phenyl or substituted phenyl; and Y represents a group represented by the formula Y1-Y2-Ar2 or Y3-Y4(Ar5)-Ar6 or a pharmaceutically acceptable salt of the derivative. The novel piperazine derivative has MC4 receptor antagonistic activity.
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