发明申请
- 专利标题： Sulfonamides as potassium channel blockers
- 专利标题（中）： 磺酰胺作为钾通道阻滞剂
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申请号： US10641686申请日： 2003-08-14
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公开(公告)号： US20060094721A9公开(公告)日： 2006-05-04
- 发明人: Grant McNaughton-Smith , Aimee Reed , Robert Atkinson
- 申请人： Grant McNaughton-Smith , Aimee Reed , Robert Atkinson
- 申请人地址： US NC Durham
- 专利权人： Icagen, Inc.
- 当前专利权人： Icagen, Inc.
- 当前专利权人地址： US NC Durham
- 主分类号： A61K31/53
- IPC分类号： A61K31/53 ; A61K31/506 ; A61K31/501 ; A61K31/497 ; A61K31/427
摘要：
Compounds, compositions and methods are provided which are useful in the treatment of diseases through the modulation of potassium ion flux through voltage-dependent potassium channels. More particularly, the invention provides sulfonamides, and compositions and methods utilizing sulfonamides that are useful in the treatment of diseases by blocking potassium channels associated with the onset or recurrence of the indicated conditions. Exemplary diseases treatable with the compounds, compositions and methods of the invention include sickle cell disease and glaucoma.
公开/授权文献
- US07119112B2 Sulfonamides as potassium channel blockers 公开/授权日：2006-10-10
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