发明申请
US20060100268A1 Method of treating atherosclerosis or restenosis using microtube stabilizing agent
审中-公开
使用微管稳定剂治疗动脉粥样硬化或再狭窄的方法
- 专利标题: Method of treating atherosclerosis or restenosis using microtube stabilizing agent
- 专利标题(中): 使用微管稳定剂治疗动脉粥样硬化或再狭窄的方法
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申请号: US11304362申请日: 2005-12-14
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公开(公告)号: US20060100268A1公开(公告)日: 2006-05-11
- 发明人: James Kinsella , Steven Sollott
- 申请人: James Kinsella , Steven Sollott
- 专利权人: The Govt. of U.S.A. as represented by the Secretary of the Dept. of Health & Human Services
- 当前专利权人: The Govt. of U.S.A. as represented by the Secretary of the Dept. of Health & Human Services
- 主分类号: A61K31/337
- IPC分类号: A61K31/337
摘要:
The present invention is a method of preventing or reducing atherosclerosis or restenosis, and a pharmaceutical preparation used therefor. In particular, it is a method of preventing or reducing atherosclerosis or restenosis after arterial injury by treatment with a low dose of a microtubule stabilizing agent such as taxol or a water soluble taxol derivative. The low dose used in the present invention prevents artery blockage while minimizing any negative side effects associated with the drug.
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