发明申请
- 专利标题: Transferrin fusion proteins libraries
- 专利标题(中): 转铁蛋白融合蛋白文库
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申请号: US10515429申请日: 2003-08-28
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公开(公告)号: US20060105387A1公开(公告)日: 2006-05-18
- 发明人: Christopher Prior , Andrew Turner , Homayoun Sadeghi
- 申请人: Christopher Prior , Andrew Turner , Homayoun Sadeghi
- 国际申请: PCT/US03/26779 WO 20030828
- 主分类号: C40B40/10
- IPC分类号: C40B40/10 ; C07K14/79
摘要:
Modified fusion proteins of transferrin and therapeutic proteins or peptides with increased serum half-life or serum stability are disclosed. Preferred fusion proteins include those modified so that the transferrin moiety exhibits no or reduced glycosylation, binding to iron and/or binding to the transferrin receptor.
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