![Process for preparing the antiviral agent [1S-(1alpha, 3alpha, 4beta)]-2-amino-1,9-dihydro-9-[4-hydroxy-3-(hydroxymethyl)-2-methylenecyclopentyl]-6H-purin-6-one](/docs/US/2006-05-18/US20060106216A1/abs.jpg.600x600.jpg)
- 专利标题： Process for preparing the antiviral agent [1S-(1alpha, 3alpha, 4beta)]-2-amino-1,9-dihydro-9-[4-hydroxy-3-(hydroxymethyl)-2-methylenecyclopentyl]-6H-purin-6-one
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申请号： US11311598申请日： 2005-12-19
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公开(公告)号： US20060106216A1公开(公告)日： 2006-05-18
- 发明人: Yadagiri Pendri , Chung-Pin Chen , Jing Liang , Shaopeng Wang , Milan Stojanovic , Richard Polniaszek , John Thottathil , Dhileepkumar Krishnamurty
- 申请人： Yadagiri Pendri , Chung-Pin Chen , Jing Liang , Shaopeng Wang , Milan Stojanovic , Richard Polniaszek , John Thottathil , Dhileepkumar Krishnamurty
- 主分类号： C07D473/10
- IPC分类号： C07D473/10
![Process for preparing the antiviral agent [1S-(1alpha, 3alpha, 4beta)]-2-amino-1,9-dihydro-9-[4-hydroxy-3-(hydroxymethyl)-2-methylenecyclopentyl]-6H-purin-6-one](/abs-image/US/2006/05/18/US20060106216A1/abs.jpg.150x150.jpg)
摘要：
Processes are disclosed for preparing the antiviral agent entecavir. A resin adsorption process for the isolation and purification of entecavir is also disclosed. Various intermediates useful in the preparation of entecavir are also disclosed.
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