发明申请
- 专利标题: Nucleic acid end-labeling reagents
- 专利标题(中): 核酸末端标记试剂
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申请号: US11290802申请日: 2005-11-29
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公开(公告)号: US20060115848A1公开(公告)日: 2006-06-01
- 发明人: Andrei Blokhin , Paul Slattum , Vladimir Budker
- 申请人: Andrei Blokhin , Paul Slattum , Vladimir Budker
- 主分类号: C12Q1/68
- IPC分类号: C12Q1/68 ; C07K14/435 ; C07H21/04 ; C07D403/02 ; A61K38/16
摘要:
Compounds and methods are provided for covalent end-labeling of polynucleotides. Incorporation of a nucleic acid affinity group improves the efficiency of reaction of aldehyde reactive groups with the nucleic acid leading to more efficient labeling.
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